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タイトル
  • en Chamaejasmins, cytotoxic guaiane sesquiterpenes from the root of Stellera chamaejasme L.
作成者
    • en Ahmed H.H. , El-Desoky
    • en Eguchi,Keisuke
    • en Kato, Hikaru
    • en Kishimoto, Naoki
    • en Misumi, Shogo
    • en Watanabe, Takashi
    • en Tsukamoto, Sachiko
権利情報
  • en (C) 2020 This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
主題
  • NDC 471.72
  • NDC 499.3
  • Other en Sesquiterpene
  • Other en Stellera chamaejasme L.
  • Other en Chamaejasmin
  • Other en Cytotoxicity
内容注記
  • Abstract en Four new guaiane-type sesquiterpenes, chamaejasmins A-D (1-4), were isolated from the root of Stellera camaejasme L. collected in Nepal, together with two known terpenes, stelleraguaianone B (5) and 1α,7α,10αH-guaia-4,11-dien-3-one (6). The structures of 1-4 including their absolute configurations were determined by extensive 2D NMR analyses, mass spectroscopy, and TDDFT calculations of their 13C chemical shifts and ECD spectra. Chamaejasmin A (1) showed cytotoxicity against HeLa cells with an IC50 value of 6.3 μM.
出版者 en Elsevier
日付
    Issued2020-10
言語
  • eng
資源タイプ journal article
出版タイプ AM
資源識別子 HDL http://hdl.handle.net/2298/00043537 , URI https://kumadai.repo.nii.ac.jp/records/31913
関連
  • isVersionOf DOI https://doi.org/10.1016/j.fitote.2020.104714
収録誌情報
    • PISSN 0367-326X
      • en Fitoterapia
      • 巻146 開始ページ104714
ファイル
コンテンツ更新日時 2023-10-20