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タイトル
  • Potentially virulent Newcastle disease viruses are maintained in migratory waterfowl populations
作成者

TAKAKUWA, Hiroki

ITO, Toshihiro

TAKADA, Ayato

OKAZAKI, Katsunori

KIDA, Hiroshi

主題
  • Other Chick Embryo
  • Other Newcastle Disease Virus
  • Other Viral Fusion Proteins
  • Other Virulence
  • Other Phylogeny
  • NDC 649
内容注記
Other
  • Forty-seven Newcastle disease virus (NDV) strains isolated from fecal samples of waterfowls in Alaska and Siberia from 1991 to 1996 were analyzed for their virulence. None of the viruses formed plaques on MDBK cells in the absence of trypsin. Of these, 29 strains showed virulent character by the mean death time with the minimum lethal dose in chicken embryos comparable to velogenic NDV strains, Of the 29 strains, 11 were sequenced for their fusion protein (F) gene. The results showed that 5 of them contained a pair of dibasic amino acids at the cleavage site of the F, which is of a virulent type. The present results suggest that potentially virulent strains of NDV are maintained in migratory waterfowl populations in nature, and that some of those may be transmitted to domestic poultry and acquire pathogenicity during passages in chicken population.
出版者The Graduate School of Veterinary Medicine
日付 Issued 1998-02-27
言語eng
資源タイプdepartmental bulletin paper
出版タイプVoR
資源識別子 URI http://hdl.handle.net/2115/2613 , DOI https://doi.org/10.14943/jjvr.45.4.207
ID

JaLC10.14943/jjvr.45.4.207

収録誌情報
    • NCID AA0069128X
    • ISSN 0047-1917
    • Japanese Journal of Veterinary Research
    45(4), 207-215
ファイル
コンテンツ更新日時2019-04-25T02:06:05Z