タイトル |
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Effect of chondroitin sulfate and hyaluronic acid on gene expression in a three-dimensional culture of chondrocytes
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作成者 |
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アクセス権 |
open access |
主題 |
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Other
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chondrocyte
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Other
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chondroitin sulfate
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Other
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hyaluronic acid
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Other
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RT-PCR
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NDC
481
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内容注記 |
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Abstract
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The effect of glycosaminoglycan addition on a three-dimensional (3D) culture of porcine chondrocyte cells was investigated with a view to use in cartilage regenerative medicine. Chondroitin sulfate C increased the mRNA expression of type 2 collagen, while chondroitin sulfate A did not. Hyaluronic acid of high molecular weight markedly decreased the mRNA expression of both aggrecan and type 2 collagen, although hyaluronic acid of low molecular weight showed no apparent effect.
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出版者 |
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The Society for Biotechnology, Japan
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日付 |
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言語 |
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資源タイプ |
journal article |
出版タイプ |
AM |
資源識別子 |
HDL
http://hdl.handle.net/2115/14716
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関連 |
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URI
http://www.sbj.or.jp/
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isVersionOf
DOI
https://doi.org/10.1263/jbb.100.123
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PMID
16233863
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収録誌情報 |
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PISSN
1389-1723
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EISSN
1347-4421
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en
Journal of Bioscience and Bioengineering
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巻100
号1
開始ページ123
終了ページ126
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ファイル |
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コンテンツ更新日時 |
2023-07-26 |