Differences in morphological features and minimum apparent diffusion coefficient values among breast cancer subtypes using 3-tesla MRI

Kato Fumi; Kudo Kohsuke; Yamashita Hiroko; Wang Jeff; Hosoda Mitsuchika; Hatanaka Kanako C.; Mimura Rie; Oyama-Manabe Noriko; Shirato Hiroki

タイトル	en Differences in morphological features and minimum apparent diffusion coefficient values among breast cancer subtypes using 3-tesla MRI
作成者	en Kato, Fumi NRID 1000080399865 en Kudo, Kohsuke NRID 1000010374232 en Yamashita, Hiroko NRID 1000070332947 en Wang, Jeff en Hosoda, Mitsuchika NRID 1000040443931 en Hatanaka, Kanako C. en Mimura, Rie en Oyama-Manabe, Noriko NRID 1000070463742 en Shirato, Hiroki NRID 1000020187537
アクセス権	open access
権利情報	en © 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ http://creativecommons.org/licenses/by-nc-nd/4.0/ en Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
主題	Other en Breast cancer subtypes Other en Magnetic resonance imaging Other en Diffusion weighed imaging Other en Ki-67 NDC 490
内容注記	Abstract en Purpose: To compare the morphology and minimum apparent diffusion coefficient (ADC) values among breast cancer subtypes. Methods: Ninety-three patients, who underwent breast MRI and collectively had 98 pathologically proven invasive carcinomas, were enrolled. Morphology was evaluated according to BIRADS-MRI. Minimum ADC was measured. Morphology and minimum ADC were compared among subtypes. Multivariate logistic regression analyses were used to identify the characteristics associated with different subtypes. Results: Oval/round shape was significantly associated with triple-negative (TN) cancer (TN vs. non-TN: 90.9% vs. 45.2%; p = 0.0123). Rim enhancement was significantly less frequent in Luminal A (Luminal A vs. non-Luminal A: 34.2% vs. 76.1%; p = 0.0003). The minimum ADC of Luminal A was significantly higher than that of Luminal B (HER2-negative) (834 vs. 748 x 10^-6 mm2/s; p <0.025). The minimum ADC of the TN-special type was significantly higher than that of TN-ductal (997 vs. 702 x 10^-6 mm2/s; p <0.025). On the multivariate analysis comparing the characteristics associated with Luminal A vs. Luminal B (HER2-negative), the internal enhancement characteristics of the mass and minimum ADC were significant factors. Conclusion: Morphology and minimum ADC would be useful in distinguishing breast cancer subtypes.
出版者	en Elsevier
日付	Issued2016-01
言語	eng
資源タイプ	journal article
出版タイプ	AM
資源識別子	HDL http://hdl.handle.net/2115/63971
関連	isVersionOf DOI https://doi.org/10.1016/j.ejrad.2015.10.018 PMID 26724653
収録誌情報	PISSN 0720-048X en European journal of radiology 巻85 号1 開始ページ96 終了ページ102
ファイル	fulltext manuscript.pdf 1.48 MB (application/pdf) Issued2016-01
コンテンツ更新日時	2023-07-26