Risk Factors for Lower Urinary Tract Dysfunction and Symptoms After Successful Renal Transplantation

Mitsui Takahiko; Moriya Kimihiko; Morita Ken; Iwami Daiki; Kitta Takeya; Kanno Yukiko; Takeda Masayuki; Shinohara Nobuo

タイトル	en Risk Factors for Lower Urinary Tract Dysfunction and Symptoms After Successful Renal Transplantation
作成者	en Mitsui, Takahiko NRID 1000090421966 en Moriya, Kimihiko NRID 1000020374233 en Morita, Ken en Iwami, Daiki NRID 1000080581115 en Kitta, Takeya NRID 1000040374441 en Kanno, Yukiko en Takeda, Masayuki en Shinohara, Nobuo NRID 1000090250422
アクセス権	open access
権利情報	https://creativecommons.org/licenses/by-nc-nd/4.0/ en Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
主題	Other en Diabetes Mellitus Other en Kidney Transplantation Other en Lower Urinary Tract Symptoms Other en Risk Factors Other en Urinary Bladder, Overactive Other en Urinary Tract Physiological Phenomena NDC 490
内容注記	Abstract en BACKGROUND: We investigated risk factors for lower urinary tract (LUT) dysfunction and LUT symptoms in patients who successfully underwent renal transplantation (RTX). MATERIAL AND METHODS: Ninety-five patients (54 males and 41 females) undergoing RTX (median age: 45 years old) at Hokkaido University Hospital were included in this study. Uroflowmetry (UFM), postvoid residual urine volume (PVR), and 24-h bladder diaries were performed. We analyzed risk factors for voiding dysfunction, urinary frequency, polyuria, nocturia, and nocturnal polyuria after RTX using logistic regression analysis. RESULTS: End-stage renal disease arose from diabetes mellitus in 18 patients (19%). Pre-transplant dialysis had been carried out in 74 patients. Voiding dysfunction as assessed by UFM and PVR was observed in 24 patients (27%). Based on the 24-h bladder diaries, we identified frequent micturition in 29 patients (35%), polyuria in 44 (54%), nocturia in 30 (37%), and nocturnal polyuria in 46 (56%). A multivariable logistic regression analysis revealed that diabetes mellitus, which may cause autonomic disorders, was a risk factor for voiding dysfunction and nocturnal polyuria. A risk factor for frequent micturition and nocturia was older age at RTX. Being female was a risk factor for polyuria, which suggested that fluid intake in relation to body weight was higher in females. CONCLUSIONS: LUT dysfunction and LUT symptoms were not uncommon in patients who successfully underwent RTX. LUT dysfunction and LUT symptoms need to be considered in patients with risk factors such as diabetes mellitus, older age at RTX, and being female, even after successful RTX.
出版者	en International Scientific Information
日付	Issued2015-12-24
言語	eng
資源タイプ	journal article
出版タイプ	VoR
資源識別子	HDL http://hdl.handle.net/2115/64543
関連	isIdenticalTo DOI https://doi.org/10.12659/AOT.895515
収録誌情報	PISSN 1425-9524 en Annals of transplantation 巻20 開始ページ757 終了ページ763
ファイル	fulltext E26Iwami_AnnTransplant20_757.pdf 178.57 KB (application/pdf) Issued2015-12-24
コンテンツ更新日時	2023-07-26