Analysis of treatment process time for real-time-image gated-spot-scanning proton-beam therapy (RGPT) system

Yoshimura Takaaki; Shimizu Shinichi; Hashimoto Takayuki; Nishioka Kentaro; Katoh Norio; Inoue Tetsuya; Taguchi Hiroshi; Yasuda Koichi; Matsuura Taeko; Takao Seishin; Tamura Masaya; Ito Yoichi M.; Matsuo Yuto; Tamura Hiroshi; Horita Kenji; Umegaki Kikuo; Shirato Hiroki

タイトル	en Analysis of treatment process time for real-time-image gated-spot-scanning proton-beam therapy (RGPT) system
作成者	en Yoshimura, Takaaki NRID 1000070807742 en Shimizu, Shinichi NRID 1000050463724 en Hashimoto, Takayuki NRID 1000060400678 en Nishioka, Kentaro NRID 1000080463743 en Katoh, Norio NRID 1000080572495 en Inoue, Tetsuya NRID 1000010431363 en Taguchi, Hiroshi NRID 1000090374454 en Yasuda, Koichi NRID 1000000431362 en Matsuura, Taeko NRID 1000090590266 en Takao, Seishin NRID 1000010614216 en Tamura, Masaya NRID 1000040504775 en Ito, Yoichi M. NRID 1000010334236 en Matsuo, Yuto en Tamura, Hiroshi en Horita, Kenji en Umegaki, Kikuo NRID 1000040643193 en Shirato, Hiroki NRID 1000020187537
アクセス権	metadata only access
権利情報	https://creativecommons.org/licenses/by/4.0/ en Creative Commons Attribution 4.0 International
主題	Other en beam-delivery efficiency Other en interplay effect Other en organ motion Other en spot-scanning proton-beam therapy Other en treatment time NDC 492
内容注記	Abstract en We developed a synchrotron-based real-time-image gated-spot-scanning proton-beam therapy (RGPT) system and utilized it to clinically operate on moving tumors in the liver, pancreas, lung, and prostate. When the spot-scanning technique is linked to gating, the beam delivery time with gating can increase, compared to that without gating. We aim to clarify whether the total treatment process can be performed within approximately 30 min (the general time per session in several proton therapy facilities), even for gated-spot-scanning proton-beam delivery with implanted fiducial markers. Data from 152 patients, corresponding to 201 treatment plans and 3577 sessions executed from October 2016 to June 2018, were included in this study. To estimate the treatment process time, we utilized data from proton beam delivery logs during the treatment for each patient. We retrieved data, such as the disease site, total target volume, field size at the isocenter, and the number of layers and spots for each field, from the treatment plans. We quantitatively analyzed the treatment process, which includes the patient load (or setup), bone matching, marker matching, beam delivery, patient unload, and equipment setup, using the data obtained from the log data. Among all the cases, 90 patients used the RGPT system (liver: n = 34; pancreas: n = 5; lung: n = 4; and prostate: n = 47). The mean and standard deviation (SD) of the total treatment process time for the RGPT system was 30.3 +/- 7.4 min, while it was 25.9 +/- 7.5 min for those without gating treatment, excluding craniospinal irradiation (CSI; head and neck: n = 16, pediatric: n = 31, others: n = 15); for CSI (n = 11) with two or three isocenters, the process time was 59.9 +/- 13.9 min. Our results demonstrate that spot-scanning proton therapy with a gating function can be achieved in approximately 30-min time slots.
出版者	en John Wiley & Sons
日付	Issued2020-02
言語	eng
資源タイプ	journal article
出版タイプ	NA
資源識別子	HDL http://hdl.handle.net/2115/76761
関連	isIdenticalTo DOI https://doi.org/10.1002/acm2.12804 PMID 31886616
収録誌情報	EISSN 1526-9914 NCID AA12034060 en Journal of applied clinical medical physics 巻21 号2 開始ページ38 終了ページ49
コンテンツ更新日時	2023-07-26