• ja Genotype Determination of Hepatitis C Virus Strains in Malaysia
  • Institute of Tropical Medicine, Nagasaki University
    • Zheng, Wei-Yun
    • Hasebe, Futoshi
    • Ali, Ayub
    • Sinniah, Mangalam
    • Saraswathy, T. S.
    • Ooi, Beng Geok
    • Igarashi, Akira
  • Other Out of 12 patient sera obtained from Malaysia, seven sera (7/12) were found to contain hepatitis C virus (HCV) genome by nested RT-PCR with universal HCV specific primers which were derived from 5' noncoding region (5' NCR). Genotype determination of these 7 Malaysian HCV strains were carried out both by subtype-specific core amplification system (Okamoto et al., 1992 and 1993) and sequencing in the 5' NCR. Four Malaysian strains were major genotype 1 (two of subtype II/1b, one of subtype I/1a and one of co-infection with I/1a + II/1b). The genotypes of 3 remaining strains were determined as major genotype 3 by nucleotide sequences in the 5' NCR. The results showed that HCV major genotype 1, 2 and 3 are common in the world, especially in Asian countries including Malaysia.
  • Other identifier:熱帯医学 Tropical medicine 38(2). p51-60, 1996
Publisher 長崎大学熱帯医学研究所
    Created2020-12-24 , Issued1996-06-30
  • eng
Resource Type departmental bulletin paper
Version Type NA
Identifier URI
    • NCID AN00199644
    • ISSN 0385-5643
      • 熱帯医学 Tropical medicine 38(2), 51-60
Oaidate 2021-02-17