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Title
  • A NEUTRAL SUGAR IS RESPONSIBLE FOR SEROVAR SPECIFICITY OF THE ANTIGENIC DETERMINANT OF LEPTOSPIRA INTERROGANS SEROVAR CANICOLA
Creator

KASHIWASE, Hiroto

ONO, Etsuro

YANAGAWA, Ryo

SHIMIZU, Yukio

KIDA, Hiroshi

Subject
  • Other Leptospira
  • Other glycolipid
  • Other antigen
  • Other determinant
  • Other sugar
  • NDC 649
Description
Other
  • To provide information on the chemical structures of antigenic determinants of leptospira, glycolipids of Leptospira interrogans serovar canicola strain Hond Utrecht IV (Ut-IV) and its antigenic variant selected in the presence of a serovar-specific monoclonal antibody were compared physicochemically. Gasliquid chromatography-mass spectrometry analysis revealed that the glycolipid of Ut-IV contained 6 neutral sugar species ; rhamnose, mannose, galactose, glucose, and unknown sugars III and IV, in addition to unknown sugars I and II that had been previously reported. On the other hand, the glycolipid of the variant lacked unknown sugar III, suggesting that this sugar is responsible for the serovar-specific antigenic determinant.
PublisherThe Graduate School of Veterinary Medicine
Date Issued 1994-08-31
Languageeng
NIItypedepartmental bulletin paper
VersiontypeVoR
Identifier URI http://hdl.handle.net/2115/2471 , DOI https://doi.org/10.14943/jjvr.42.2.103
ID

JaLC10.14943/jjvr.42.2.103

Journal
    • NCID AA0069128X
    • ISSN 0047-1917
    • Japanese Journal of Veterinary Research
    42(2), 103-108
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Oaidate2019-04-25T01:30:40Z