Title |
-
en
Memory and Decision Making in the Frontal Cortex during Visual Motion Processing for Smooth Pursuit Eye Movements
|
Creator |
|
Accessrights |
open access |
Subject |
-
Other
en
Frontal cortex
-
Other
en
Supplementary eye fields
-
Other
en
Smooth pursuit
-
Other
en
Visual motion
-
Other
en
Memory
-
Other
en
Decision-making
-
Other
en
Movement preparation, Monkey
-
NDC
491
|
Description |
-
Abstract
en
Cortical motor areas are thought to contribute "higher-order processing" but what that processing might include is unknown. Previous studies of the smooth pursuit-related discharge of supplementary eye field (SEF) neurons did not distinguish activity associated with the preparation for pursuit from discharge related to processing or memory of the target motion signals. Using a new, memory-based task, which was designed to separate these components, we show that the SEF contains signals coding retinal image-slip-velocity, memory and assessment of visual motion-direction, the decision of whether or not to pursue, and the preparation for pursuit eye movements. Bilateral muscimol injection into SEF resulted in directional errors in smooth pursuit, errors of whether or not to pursue, and impairment of initial correct eye movements. These results suggest an important role for the SEF in memory and assessment of visual motion-direction and the programming of appropriate pursuit eye movements.
|
Publisher |
en
Cell Press
|
Date |
|
Language |
|
Resource Type |
journal article |
Version Type |
AM |
Identifier |
HDL
http://hdl.handle.net/2115/38756
|
Relation |
-
isVersionOf
DOI
https://doi.org/10.1016/j.neuron.2009.05.010
|
Journal |
-
-
en
Neuron
-
Volume Number62
Issue Number5
Page Start717
Page End732
|
File |
|
Oaidate |
2023-07-26 |