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Title
  • en Effects of parabens on apoptosis induced by serum-free medium.
Creator
Accessrights open access
Rights
  • en This is an Author's Accepted Manuscript of an article published in Journal of Environmental Science and Health, Part B Pesticides, Food Contaminants, and Agricultural Wastes, Vol. 47, Iss. 3, 2012, copyright Taylor & Francis, available online at: http://www.tandfonline.com/10.1080/03601234.2012.634341.
Subject
  • Other en PC12 cell
  • Other en endocrine disrupter
  • Other en food additives
  • Other en apoptotic factors
  • Other en methylparaben
  • Other en butylparaben
  • NDC 498
Description
  • Abstract en Alkyl esters of p-hydroxybenzoic acids (parabens), an endocrine disrupter, are used as preservatives in cosmetics and foods. In this study, to understand the relationship between parabens and differentiation in infants, the effects of parabens on apoptosis induced by serum deprivation in PC12 cells were investigated. In addition, apoptosis-related factors were assayed. As results, a tendency toward enhancement of apoptosis was observed in the cells cultured in the serum-free medium with methylparaben, and this tendency was suggested to be related to the contents of BAD, a pro-apoptotic protein. Butylparaben did not show any tendency to enhance apoptosis.
Publisher en Taylor & Francis
Date
    Issued2012-03
Language
  • eng
Resource Type journal article
Version Type AM
Identifier HDL http://hdl.handle.net/2115/52989
Relation
  • isVersionOf DOI https://doi.org/10.1080/03601234.2012.634341
  • PMID 22375591
Journal
    • PISSN 0360-1234
    • EISSN 1532-4109
    • NCID AA00697424
      • en Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes
      • Volume Number47 Issue Number3 Page Start196 Page End204
File
Oaidate 2023-07-26