Title |
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11C-Methionine positron emission tomography may monitor the activity of encephalitis
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Accessrights |
open access |
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Acta Radiol, December 2012, 53(10), pp.1155-1157, doi: 10.1258/ar.2012.120382. This is the final draft, after peer-review, of a manuscript published in Acta Radiologica. The definitive version, detailed above, is available online at www.rsmjournals.com.
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Subject |
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Other
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Encephalitis
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Other
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positron emission tomography
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Other
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methionine
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Other
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therapy monitoring
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NDC
492
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Description |
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Abstract
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Encephalitis is generally diagnosed by clinical symptoms, cerebrospinal fluid examination, and imaging studies including CT, MR imaging and perfusion single photon emission tomography (SPECT). However, the role of positron emission tomography (PET) in diagnosis of encephalitis remains unclear. A 49-year-old woman presenting with coma and elevated inflammatory reaction was diagnosed as having encephalitis according to slow activity on electroencephalogram, broad cortical lesion in MR fluid attenuated inversion recovery image, and increased blood flow demonstrated by SPECT. PET revealed increased accumulation of 11C-methionine (MET) in the affected brain tissues. After the symptom had improved two months later, the accumulation of MET as well as the abnormal findings of MR imaging and SPECT was normalized. This case indicated that MET PET may monitor the activity of encephalitis.
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Publisher |
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Royal Society of Medicine Press
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Date |
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Language |
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Resource Type |
journal article |
Version Type |
AM |
Identifier |
HDL
http://hdl.handle.net/2115/52053
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Relation |
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isVersionOf
DOI
https://doi.org/10.1258/ar.2012.120382
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PMID
22993272
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Journal |
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Acta Radiologica
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Volume Number53
Issue Number10
Page Start1155
Page End1157
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File |
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Oaidate |
2023-07-26 |