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Title	en POLYFLUOROALKYLATION OF CARBONYL COMPOUNDS BY POLYFLUOROALKYL ANIONS GENERATED FROM POLYFLUOROCARBOXAMIDES
Creator	en Wakita, Natshumi en Hara, Shoji NRID 1000020109490
Accessrights	open access
Subject	NDC 430
Description	Abstract en Polyfluoroalkyl anions, generated by reduction of (polyfluoroalkanoyl)piperidines with Et3BHK, were used for the polyfluoroalkylation of carbonyl compounds. Trifluoromethylation of aromatic aldehydes proceeded in good yields, and that of aliphatic aldehydes afforded a moderate yield. In contrast, the yield was low when the reaction involved benzophenone. Pentafluoroethylation and octafluorobutylation of aldehydes were also carried out by using the corresponding (polyfluoroalkanoyl)piperidines, which were prepared from commercially available polyfluorocompounds. The (polyfluoroalkanoyDpiperidines were also prepared through polyfluorination, and were used in the polyfluoroalkylation of aldehydes.
Publisher	en Pergamon-elsevier science ltd
Date	Issued2014-01-27
Language	eng
Resource Type	journal article
Version Type	SMUR
Identifier	HDL http://hdl.handle.net/2115/54926
Relation	isVersionOf DOI https://doi.org/10.3987/COM-13-S(S)84
Journal	PISSN 0385-5414 en Heterocycles Volume Number88 Issue Number2 Page Start1201 Page End1212
File	fulltext POLYFLUOROALKYLATION OF CARBONYL COMPOUNDS BY POLYFLUOROALKYL ANIONS GENERATED FROM POLYFLUOROCARBOXAMIDES.pdf 642.07 KB (application/pdf) Issued2014-01-27
Oaidate	2023-07-26