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Title
  • en Three-dimensional transillumination image reconstruction for small animal with new scattering suppression technique
Creator
    • en Trung Nghia Tran
    • en Yamamoto, Kohei
    • en Namita, Takeshi
Accessrights open access
Rights
  • en This paper was published in Biomed. Opt. Express and is made available as an electronic reprint with the permission of OSA. The paper can be found at the following URL on the OSA website: http://www.opticsinfobase.org/boe/abstract.cfm?uri=boe-5-5-1321. Systematic or multiple reproduction or distribution to multiple locations via electronic or other means is prohibited and is subject to penalties under law.
Subject
  • Other en deconvolution
  • Other en image reconstruction techniques
  • Other en medical and biological imaging
  • Other en tomography
  • Other en turbid media
  • NDC 548
Description
  • Abstract en To realize three-dimensional (3D) optical imaging of the internal structure of an animal body, we have developed a new technique to reconstruct optical computed tomography (optical CT) images from two-dimensional (2D) transillumination images. In transillumination imaging of an animal body using near-infrared light, the image is blurred because of the strong scattering in the tissue. To overcome this problem, we propose a novel technique to apply the point spread function (PSF) for a light source located inside the medium to the transilluminated image of light-absorbing structure. The problem of the depth-dependence of PSF was solved in the calculation of the projection image in the filtered back-projection method. The effectiveness of the proposed technique was assessed in the experiments with a model phantom and a mouse. These analyses verified the feasibility of the practical 3D imaging of the internal light-absorbing structure of a small animal. (C) 2014 Optical Society of America
Publisher en Optical Society
Date
    Issued2014-05-01
Language
  • eng
Resource Type journal article
Version Type VoR
Identifier HDL http://hdl.handle.net/2115/56750
Relation
  • isIdenticalTo DOI https://doi.org/10.1364/BOE.5.001321
Journal
    • PISSN 2156-7085
      • en Biomedical Optics Express
      • Volume Number5 Issue Number5 Page Start1321 Page End1335
File
Oaidate 2023-07-26