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Title
  • en Comparison of cardiac output measurements using transpulmonary thermodilution and conventional thermodilution techniques in anaesthetized dogs with fluid overload
Creator
    • en Endo, Yusuke
    • en Hanazono, Kiwamu
    • en Ishizuka, Tomohito
    • en Tamura, Jun
    • en Miyoshi, Kenjiro
    • en Sano, Tadashi
Accessrights open access
Rights
  • en This is the peer reviewed version of the following article: Itami T, Endo Y, Hanazono K et al. (2015) Comparison of cardiac output measurements using transpulmonary thermodilution and conventional thermodilution techniques in anaesthetized dogs with fluid overload. Vet Anaesth Analg 43, 388-396, which has been published in final form at http://dx.doi.org/10.1111/vaa.12331. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Subject
  • Other en cardiac output
  • Other en dog
  • Other en fluid overload
  • Other en thermodilution
  • Other en transpulmonary
  • NDC 649
Description
  • Abstract en Objective: To evaluate the agreement between cardiac output (CO) values obtained using a transpulmonary thermodilution technique (TPTDCO) and conventional thermodilution technique (TDCO) in anaesthetized dogs with fluid overload. Study design: Prospective experimental study. Animals: Six healthy Beagle dogs aged 7-8years. Methods: Dogs were anaesthetized with sevoflurane in oxygen, and catheters were inserted for TPTDCO and TDCO measurement. After instrumentation, baseline CO was measured using each technique at a central venous pressure (CVP) of 3-7mmHg. Dogs were subsequently administered lactated Ringer's solution and 6% hydroxyethyl starch to induce fluid overload. CO measurements were obtained using each technique at CVP values of 8-12mmHg, 13-17mmHg, 18-22mmHg and 23-27mmHg. Agreements between CO measurements obtained with the respective techniques were analysed using Dunnett's test, Pearson's correlation coefficient and Bland-Altman analysis. Results: Thirty pairs of CO values were obtained, ranging from 1.45Lminute(-1) to 4.69Lminute(-1) for TPTDCO and from 1.30Lminute(-1) to 4.61Lminute(-1) for TDCO. TPTDCO and TDCO values correlated strongly (r(2)=0.915, p<0.001). The bias and mean relative bias between TPTDCO and TDCO were 0.260.30Lminute(-1) (limits of agreement -0.29 to 0.81Lminute(-1)) and 9.7%, respectively. Conclusions and clinical relevance: TPTDCO and TDCO measurements obtained in anaesthetized dogs during fluid overload exhibited good agreement. Accordingly, transpulmonary thermodilution provides an accurate measurement of CO in dogs with fluid overload.
Publisher en Wiley-Blackwell
Date
    Issued2016-07
Language
  • eng
Resource Type journal article
Version Type AM
Identifier HDL http://hdl.handle.net/2115/66557
Relation
  • isVersionOf DOI https://doi.org/10.1111/vaa.12331
  • PMID 26671761
Journal
    • PISSN 1467-2987
    • EISSN 1467-2995
    • NCID AA11560760
      • en Veterinary Anaesthesia and Analgesia
      • Volume Number43 Issue Number4 Page Start388 Page End396
File
Oaidate 2023-07-26