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STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation

Nakamura, Takashi | Sato, Takanori | Endo, Rikito | Sasaki, Shun | Takahashi, Naomichi | Sato, Yusuke | Hyodo, Mamoru | Hayakawa, Yoshihiro | Harashima, Hideyoshi

Hokkaido University Collection of Scholarly and Academic PapersHokkaido University

Dual Effect of Organogermanium Compound THGP on RIG-I-Mediated Viral Sensing and Viral Replication during Influenza a Virus Infection

Baidya, Sunanda | Nishimoto, Yoko | Sato, Seiichi | Shimada, Yasuhiro | Sakurai, Nozomi | Nonaka, Hirotaka | Noguchi, Koki | Kido, Mizuki | Tadano, Satoshi | Ishikawa, Kozo | Li, Kai | Okubo, Aoi | Yamada, Taisho | Orba, Yasuko | Sasaki, Michihito | Sawa, Hirofumi | Miyamoto, Hiroko | Takada, Ayato | Nakamura, Takashi | Takaoka, Akinori

Hokkaido University Collection of Scholarly and Academic PapersHokkaido University

The silencing of indoleamine 2,3-dioxygenase 1 (IDO1) in dendritic cells by siRNA-loaded lipid nanoparticles enhances cell-based cancer immunotherapy

Endo, Rikito | Nakamura, Takashi | Kawakami, Kyoko | Sato, Yusuke | Harashima, Hideyoshi

Hokkaido University Collection of Scholarly and Academic PapersHokkaido University

Liposome Microencapsulation for the Surface Modification and Improved Entrapment of Cytochrome c for Targeted Delivery

Kajimoto, Kazuaki | Katsumi, Tatsuhito | Nakamura, Takashi | Kataoka, Masatoshi | Harashima, Hideyoshi

Hokkaido University Collection of Scholarly and Academic PapersHokkaido University

Modifying Antigen-Encapsulating Liposomes with KALA Facilitates MHC Class I Antigen Presentation and Enhances Anti-tumor Effects

Miura, Naoya | Akita, Hidetaka | Tateshita, Naho | Nakamura, Takashi | Harashima, Hideyoshi

Hokkaido University Collection of Scholarly and Academic PapersHokkaido University

Modifying Cationic Liposomes with Cholesteryl-PEG Prevents Their Aggregation in Human Urine and Enhances Cellular Uptake by Bladder Cancer Cells

Nakamura, Takashi | Noma, Yosuke | Sakurai, Yu | Harashima, Hideyoshi

Hokkaido University Collection of Scholarly and Academic PapersHokkaido University

A lipid nanoparticle for the efficient delivery of siRNA to dendritic cells

Warashina, Shota | Nakamura, Takashi | Sato, Yusuke | Fujiwara, Yuki | Hyodo, Mamoru | Hatakeyama, Hiroto | Harashima, Hideyoshi

Hokkaido University Collection of Scholarly and Academic PapersHokkaido University

Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma

Nakamura, Takashi | Miyabe, Hiroko | Hyodo, Mamoru | Sato, Yusuke | Hayakawa, Yoshihiro | Harashima, Hideyoshi

Hokkaido University Collection of Scholarly and Academic PapersHokkaido University

A KALA-modified lipid nanoparticle containing CpG-free plasmid DNA as a potential DNA vaccine carrier for antigen presentation and as an immune-stimulative adjuvant

Miura, Naoya | Shaheen, Sharif M. | Akita, Hidetaka | Nakamura, Takashi | Harashima, Hideyoshi

Hokkaido University Collection of Scholarly and Academic PapersHokkaido University