| タイトル |
-
en
Development of a 3D collagen scaffold coated with multiwalled carbon nanotubes
|
| 作成者 |
|
| アクセス権 |
open access |
| 権利情報 |
-
en
This is the pre-peer reviewed version of the following article: Journal of Biomedical Materials Research, Part B, 90B(2), 2009, pp.629-634, which has been published in final form at http://dx.doi.org/10.1002/jbm.b.31327
|
| 主題 |
-
Other
en
carbon nanotubes
-
Other
en
coating
-
Other
en
collagen sponge honeycomb
-
Other
en
3D scaffolds
-
Other
en
cell culture
-
NDC
497
|
| 内容注記 |
-
Abstract
en
Carbon nanotubes (CNTs) have attractive biochemical properties such as strong cell adhesion and protein absorption, which are very useful for a cell cultivation scaffold. In this study, we prepared a multiwalled carbon nanotube-coated collagen sponge (MWCNT-coated sponge) to improve the surface properties of the collagen sponge, and its cell culturing properties were examined. The suface of the collagen sponge was homogeneously coated with MWCNTs by dispersion. MC3T3-E1 cells were cultured on and inside the MWCNT-coated sponge. The DNA content on the MWCNT-coated sponge after 1 week of culture was significantly higher than on an uncoated collagen sponge (p<0.05). There was no significant difference between the estimated ALP activity normalized by DNA quantity on the MWCNT-coated sponge and that on the uncoated collagen sponge which is well known as one of the best scaffolds for cell cultivation. In addition, the MWCNT-coated surface shows strong cell adhesion. Therefore, the MWCNT-coated collagen sponge is expected to be a useful 3D scaffold for cell cultivation.
|
| 出版者 |
en
Wiley
|
| 日付 |
|
| 言語 |
|
| 資源タイプ |
journal article |
| 出版タイプ |
AM |
| 資源識別子 |
HDL
http://hdl.handle.net/2115/38894
|
| 関連 |
-
isVersionOf
DOI
https://doi.org/10.1002/jbm.b.31327
-
PMID
19213050
|
| 収録誌情報 |
-
-
PISSN
1552-4973
-
EISSN
1552-4981
-
NCID
AA11881538
-
en
Journal of Biomedical Materials Research. Part B, Applied Biomaterials
-
巻90
号2
開始ページ629
終了ページ634
|
| ファイル |
|
| コンテンツ更新日時 |
2023-07-26 |
