| タイトル |
-
en
Polar localization and endocytic degradation of a boron transporter, BOR1, is dependent on specific tyrosine residues
|
| 作成者 |
|
| アクセス権 |
open access |
| 主題 |
-
Other
en
mineral transporter
-
Other
en
polar localization
-
Other
en
tyrosine-based signal
-
Other
en
ubiquitination
-
Other
en
membrane trafficking
-
Other
en
endocytosis
-
NDC
460
|
| 内容注記 |
-
Abstract
en
Boron (B) is essential for plants, but is toxic in excess. Plants have to strictly regulate the uptake and translocation of B. In Arabidopsis thaliana root cells, a boric acid channel, NIP5;1, and a boric acid/borate exporter, BOR1, localize to the outer (facing soil) and inner plasma membrane domains, respectively, under B limitation. The opposite polar localizations of the importer and exporter would enable plant roots to transport B efficiently towards the xylem. In addition, accumulation of the B transporters is controlled by B conditions. When plants are shifted from low to high B conditions, NIP5;1 transcript accumulation is down-regulated through mRNA degradation. The BOR1 protein is transported to the trans-Golgi network/early endosome and multivesicular body and finally degraded in the vacuole. We have recently shown that both the polar localization and the endocytic degradation of BOR1 are controlled by at least two tyrosine residues in a large loop located in the cytosol. We also showed that ubiquitination is required for the endocytic degradation of BOR1. Here, we analyzed possible involvement of an additional tyrosine residue (Y414) in the loop region and discuss the pathway of the BOR1 trafficking for polar localization and endocytic degradation of BOR1.
|
| 出版者 |
en
Taylor & Francis
|
| 日付 |
|
| 言語 |
|
| 資源タイプ |
journal article |
| 出版タイプ |
AM |
| 資源識別子 |
HDL
http://hdl.handle.net/2115/59503
|
| 関連 |
-
isVersionOf
DOI
https://doi.org/10.4161/psb.7.1.18527
|
| 収録誌情報 |
-
-
en
Plant Signaling & Behavior
-
巻7
号1
開始ページ46
終了ページ49
|
| ファイル |
|
| コンテンツ更新日時 |
2023-07-26 |
