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Title
  • A novel signaling pathway mediated by the nuclear targeting of C-terminal fragments of mammalian Patched 1.
Creator

Kagawa, Hiroki

Shino, Yuka

Kobayashi, Daigo

Demizu, Syunsuke

Shimada, Masumi

Ariga, Hiroyoshi

Kawahara, Hiroyuki

Rights
    • http://creativecommons.org/licenses/by/3.0/
Subject
  • NDC 499
  • MeSH Amino Acid Sequence
  • MeSH Animals
  • MeSH Cell Nucleus/metabolism
  • MeSH HeLa Cells
  • MeSH Humans
  • MeSH Kruppel-Like Transcription Factors/physiology
  • MeSH Mice
  • MeSH Mice, Inbred C3H
  • MeSH Molecular Sequence Data
  • MeSH Receptors, Cell Surface/chemistry
  • MeSH Receptors, Cell Surface/metabolism
  • MeSH Sequence Homology, Amino Acid
  • MeSH Signal Transduction
  • MeSH Subcellular Fractions/metabolism
  • MeSH Transcription, Genetic
Description
Other
  • Patched 1 (Ptc1) is a polytopic receptor protein that is essential for growth and differentiation. Its extracellular domains accept its ligand, Sonic Hedgehog, while the function of its C-terminal intracellular domain is largely obscure.
PublisherPloS
Date Issued 2011-04-13
Languageeng
NIItypejournal article
VersiontypeVoR
Identifier URI http://hdl.handle.net/2115/53698
Relation
  • isIdenticalTo PMID 21533246
  • isIdenticalTo DOI https://doi.org/10.1371/journal.pone.0018638
Journal
    • ISSN 1932-6203
    • PloS one
    6(4), e18638
File
Oaidate2017-10-15T15:00:00Z