Title |
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Improvement of cerebral hypometabolism after resection of radiation-induced necrotic lesion in a patient with cerebral arteriovenous malformation
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Creator |
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Accessrights |
open access |
Rights |
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Subject |
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Intracranial arteriovenous malformation
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stereotactic radiosurgery
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radiation-induced necrosis
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brain edema
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Other
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F-18 fluorodeoxyglucose
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Other
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positron emission tomography
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NDC
490
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Description |
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Abstract
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A 55-year-old woman underwent radiosurgery for a left cerebral hemisphere arteriovenous malformation (AVM) and developed radiation-induced necrosis causing a massive edema in the surrounding brain tissues. Despite various therapies, the edema expanded to the ipsilateral hemisphere and induced neurological symptoms. The radiation-induced necrotic lesion was surgically removed 4 years after radiosurgery. While the preoperative FDG PET revealed severe hypometabolism in the left cerebrum, the necrotomy significantly ameliorated the brain edema, glucose metabolism (postoperative FDG PET), and symptoms. This case indicates that radiation necrosis-induced neurological deficits may be associated with brain edema and hypometabolism, which could be reversed by appropriate necrotomy.
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Publisher |
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SAGE Publications
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Date |
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Language |
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Resource Type |
journal article |
Version Type |
VoR |
Identifier |
HDL
http://hdl.handle.net/2115/60585
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Relation |
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isIdenticalTo
DOI
https://doi.org/10.1177/2058460115584112
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Journal |
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Acta radiologica open
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Volume Number4
Issue Number6
Page Start2058460115584112
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File |
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Oaidate |
2023-07-26 |