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Title	en Primary malignant melanoma of the esophagus treated with subtotal esophagectomy : a case report
Creator	en Kuwabara, Shota en Ebihara, Yuma NRID 1000050632981 en Nakanishi, Yoshitsugu en Asano, Toshimichi en Noji, Takehiro NRID 1000010739296 en Kurashima, Yo NRID 1000040374350 en Murakami, Soichi en Nakamura, Toru NRID 1000070645796 en Tsuchikawa, Takahiro NRID 1000050507572 en Okamura, Keisuke en Shichinohe, Toshiaki NRID 1000070374353 en Hirano, Satoshi NRID 1000050322813
Accessrights	open access
Rights	http://creativecommons.org/licenses/by/4.0/ en Creative Commons Attribution 4.0 International
Subject	Other en Esophagus Other en Melanoma Other en Pathology Other en Treatment Other en Prognosis NDC 490
Description	Abstract en Background: Primary malignant melanoma of the esophagus (PMME) is a rare disease with a poor prognosis. There are few reports of early-stage cases in which tumor invasion reached the lamina propria or muscularis mucosae, as in the present case. A standard treatment for early-stage PMME has not yet been established. The present study aimed to summarize previous reports and to discuss the indications for surgical treatment of early-stage primary malignant melanoma of the esophagus. Case presentation: A 70-year-old woman with PMME was referred to our hospital. She underwent thoracoscopic and laparoscopic subtotal esophagectomy with lymphadenectomy. The resected specimen showed melanocytosis and junctional activity. Melanoma-specific antigens melan-A, S-100, and HMB45 were detected by immunohistochemical staining. The pathological diagnosis was pT1a-MM, pN0, pM0, and pStage IA. She remains alive without evidence of recurrence 39 months later. Conclusion: Subtotal esophagectomy with regional radical lymphadenectomy could be recommended to patients with early-stage primary malignant melanoma of the esophagus, and curative surgical resection could improve their prognosis.
Publisher	en BioMed Central
Date	Issued2017-12-02
Language	eng
Resource Type	journal article
Version Type	VoR
Identifier	HDL http://hdl.handle.net/2115/68335
Relation	isIdenticalTo DOI https://doi.org/10.1186/s12893-017-0326-7
Journal	PISSN 1471-2482 en BMC surgery Volume Number17 Page Start122
File	fulltext s12893-017-0326-7.pdf 2.28 MB (application/pdf) Issued2017-12-02
Oaidate	2023-07-26