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Title
  • en Relation between total shock energy and mortality in patients with implantable cardioverter-defibrillator
Creator
    • en Tenma, Taro
    • en Mitsuyama, Hirofumi
    • en Watanabe, Masaya
    • en Mizukami, Kazuya
    • en Kamada, Rui
    • en Takahashi, Masayuki
    • en Sasaki, Ryo
    • en Maeno, Motoki
    • en Okamoto, Kaori
    • en Chiba, Yuki
    • en Anzai, Toshihisa
Accessrights open access
Rights
  • en © 2018. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
  • http://creativecommons.org/licenses/by-nc-nd/4.0/
  • en Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Subject
  • Other en Total shock energy
  • Other en Implantable cardioverter-defibrillator
  • Other en Mortality
  • Other en Shock accumulation
  • Other en Low left ventricular ejection fraction
  • Other en Atrial fibrillation
  • NDC 490
Description
  • Abstract en Background: Implantable Cardioverter-Defibrillator (ICD) shocks have been associated with mortality. However, no study has examined the relation between total shock energy and mortality. The aim of this study is to assess the association of total shock energy with mortality, and to determine the patients who are at risk of this association. Methods: Data from 316 consecutive patients who underwent initial ICD implantation in our hospital between 2000 and 2011 were retrospectively studied. We collected shock energy for 3 years from the ICD implantation, and determined the relation of shock energy on mortality after adjusting confounding factors. Results: Eighty-seven ICD recipients experienced shock(s) within 3 years from ICD implantation and 43 patients had died during the follow-up. The amount of shock energy was significantly associated with all-cause death [adjusted hazard ratio (HR) 1.26 (per 100 joule increase), p < 0.01] and tended to be associated with cardiac death (adjusted HR 1.30, p = 0.08). The survival rate of patients with high shock energy accumulation (>= 182 joule) was lower (p = 0.05), as compared to low shock energy accumulation (<182 joule), likewise to no shock. Besides, the relation between high shock energy accumulation and all-cause death was remarkable in the patients with low left ventricular ejection fraction (LVEF <= 40%) or atrial fibrillation (AF). Conclusions: Increase of shock energywas related tomortality in ICD recipients. This relation was evident in patients with low LVEF or AF.
Publisher en Elsevier
Date
    Issued2018-05-15
Language
  • eng
Resource Type journal article
Version Type AM
Identifier HDL http://hdl.handle.net/2115/74003
Relation
  • isVersionOf DOI https://doi.org/10.1016/j.ijcard.2018.02.063
Journal
    • PISSN 0167-5273
      • en International journal of cardiology
      • Volume Number259 Page Start94 Page End99
File
Oaidate 2023-07-26