Body Mass Index Is an Independent Predictor of Long-Term Outcomes in Patients Hospitalized With Heart Failure in Japan

Hamaguchi Sanae; Tsuchihashi-Makaya Miyuki; Kinugawa Shintaro; Goto Daisuke; Yokota Takashi; Goto Kazutomo; Yamada Satoshi; Yokoshiki Hisashi; Takeshita Akira; Tsutsui Hiroyuki; for the JCARE-CARD Investigators

Title	en Body Mass Index Is an Independent Predictor of Long-Term Outcomes in Patients Hospitalized With Heart Failure in Japan
Creator	en Hamaguchi, Sanae en Tsuchihashi-Makaya, Miyuki en Kinugawa, Shintaro NRID 1000060399871 en Goto, Daisuke en Yokota, Takashi NRID 1000090374321 en Goto, Kazutomo en Yamada, Satoshi NRID 1000080374320 en Yokoshiki, Hisashi NRID 1000040360911 en Takeshita, Akira en Tsutsui, Hiroyuki NRID 1000070264017 en for the JCARE-CARD Investigators
Accessrights	metadata only access
Rights	https://creativecommons.org/licenses/by-nc-nd/4.0/ en Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Subject	Other en Body mass index Other en Heart failure Other en Mortality Other en Obesity Other en Prognosis NDC 490
Description	Abstract en Background: Obesity is a risk factor for cardiovascular disease (CVD) and is also associated with an increased risk of death in subjects without CVD. However, in heart failure (HF), elevated body mass index (BMI) has been shown to be associated with better prognosis, but it is unknown whether this is the case in unselected HF patients encountered in routine clinical practice in Japan. Methods and Results: The Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD) studied prospectively the characteristics and treatments in a broad sample of patients hospitalized with worsening HF and the outcomes were followed for 2.1 years. Study cohort (n=2,488) was classified into 3 groups according to baseline BMI: <20.3kg/m2 (n=829), 20.3-23.49kg/m2 (n=832), and ≥23.5kg/m2 (n=827). The mean BMI was 22.3±4.1kg/m2. Patients with higher BMI had lower rates of all-cause death, cardiac death, and rehospitalization because of worsening HF. After multivariable adjustment, the risk for all-cause death and cardiac death significantly increased with decreased BMI levels compared with patients with BMI ≥23.5kg/m2. However, BMI levels were not associated with rehospitalization for worsening HF. Conclusions: Lower BMI was independently associated with increased long-term all-cause, as well as cardiac, mortality in patients with HF encountered in routine clinical practice in Japan. (Circ J 2010; 74: 2605-2611)
Publisher	en The Japanese Circulation Society ja 社団法人日本循環器学会
Date	Issued2010
Language	eng
Resource Type	journal article
Version Type	NA
Identifier	HDL http://hdl.handle.net/2115/76970
Relation	isIdenticalTo DOI https://doi.org/10.1253/circj.CJ-10-0599
Journal	PISSN 1346-9843 EISSN 1347-4820 en Circulation Journal Volume Number74 Issue Number12 Page Start2605 Page End2611
Oaidate	2023-07-26