Predictors of Long-Term Adverse Outcomes in Elderly Patients Over 80 Years Hospitalized With Heart Failure

Hamaguchi Sanae; Kinugawa Shintaro; Goto Daisuke; Tsuchihashi-Makaya Miyuki; Yokota Takashi; Yamada Satoshi; Yokoshiki Hisashi; Takeshita Akira; Tsutsui Hiroyuki; JCARE-CARD Investigators

Title	en Predictors of Long-Term Adverse Outcomes in Elderly Patients Over 80 Years Hospitalized With Heart Failure
Creator	en Hamaguchi, Sanae en Kinugawa, Shintaro NRID 1000060399871 en Goto, Daisuke en Tsuchihashi-Makaya, Miyuki en Yokota, Takashi NRID 1000090374321 en Yamada, Satoshi en Yokoshiki, Hisashi NRID 1000040360911 en Takeshita, Akira en Tsutsui, Hiroyuki NRID 1000070264017 en JCARE-CARD Investigators
Accessrights	metadata only access
Rights	https://creativecommons.org/licenses/by-nc-nd/4.0/ en Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Subject	Other en Elderly Other en Heart failure Other en Mortality Other en Outcomes Other en Prognosis NDC 490
Description	Abstract en Background: Aging is associated with adverse outcomes in patients with cardiac diseases. Whether elderly patients hospitalized with heart failure (HF) had increased risks for mortality and rehospitalization compared with younger patients during the long-term follow-up was examined. The predictors of these adverse outcomes were also identified. Methods and Results: The Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD) studied prospectively the characteristics and treatments in a broad sample of 2,675 patients hospitalized with worsening HF and the outcomes were followed up. The majority of elderly patients were female, had lower body mass index (BMI), a higher rate of ischemic, valvular, and hypertensive heart disease as etiologies of HF, a lower estimated glomerular filtration rate (eGFR), lower hemoglobin, and higher left ventricular ejection fraction values. Even after adjustment for covariates, the elderly patients were associated with higher risks of adverse outcomes. The predictors for all-cause death were: lower eGFR, lower BMI, male sex, sustained ventricular tachycardia or fibrillation (VT/VF), and the use of diuretics at discharge. Conclusions: Among patients hospitalized with HF, elderly patients had a worse prognosis than younger patients. Lower eGFR, lower BMI, male sex, sustained VT/VF, and diuretic use were independent predictors for all-cause death in these patients with higher risk. (Circ J 2011; 75: 2403-2410)
Publisher	en The Japanese Circulation Society ja 社団法人日本循環器学会
Date	Issued2011
Language	eng
Resource Type	journal article
Version Type	NA
Identifier	HDL http://hdl.handle.net/2115/76971
Relation	isIdenticalTo DOI https://doi.org/10.1253/circj.CJ-11-0267
Journal	PISSN 1346-9843 EISSN 1347-4820 en Circulation Journal Volume Number75 Issue Number10 Page Start2403 Page End2410
Oaidate	2023-07-26