Morphological Characteristics of Genital Organ-Associated Lymphoid Tissue in the Vaginal Vestibule of Goats and Pigs

Chuluunbaatar Tsolmon; Ichii Osamu; Masum Md. Abdul; Namba Takashi; Kon Yasuhiro

Title	en Morphological Characteristics of Genital Organ-Associated Lymphoid Tissue in the Vaginal Vestibule of Goats and Pigs
Creator	en Chuluunbaatar, Tsolmon en Ichii, Osamu NRID 1000060547769 en Masum, Md. Abdul en Namba, Takashi en Kon, Yasuhiro NRID 1000010178402
Accessrights	metadata only access
Subject	Other en genital organ-associated lymphoid tissue Other en mucosa-associated lymphoid tissue Other en goat Other en pig Other en vaginal vestibule Other en lymphatic nodule Other en diffuse lymphoid tissue NDC 649
Description	Abstract en Mucosa-associated lymphoid tissue (MALT) is a specialized form of peripheral lymphoid tissue (LT), which is found on mucosal surfaces exposed to the environment. However, morphological data of these tissues in farm animals are scarce. This study investigated the gross anatomical and histological features of genital organ-associated lymphoid tissues (GOALTs) in the vaginal vestibule (VV) of healthy, non-pregnant, adult goats and pigs. Their VVs were composed of stratified squamous, non-keratinized epithelium, and various-sized dark-blue hematoxylin-positive spots were observed in whole-mount specimens, which were diffusely distributed throughout the mucosal surfaces. These spots were histologically identified as LTs and consisted of lymphatic nodules (LNs) or diffuse lymphoid tissue (DLTs). Both LNs and DLTs contained B cells, T cells, macrophages, dendritic cells, plasma cells, and high endothelial venules. Only the numbers of B cells were significantly higher in both the LNs and DLTs of pigs compared to goats. Furthermore, the surface of the VV epithelium covering the LTs was partially disrupted with a large intercellular space containing abundant connective tissue fibers with numerous lymphocytes. In conclusion, GOALTs in the VV appear to be common local immunological barriers in both examined animals. This knowledge is crucial for understanding the structures and disorders of female reproductive organs in farm animals.
Publisher	en MDPI
Date	Issued2023-01-11
Language	eng
Resource Type	journal article
Version Type	NA
Identifier	HDL http://hdl.handle.net/2115/88621
Relation	isIdenticalTo DOI https://doi.org/10.3390/vetsci10010051
Journal	EISSN 2306-7381 en Veterinary Sciences Volume Number10 Issue Number1 Page Start51
Oaidate	2023-07-26