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Title
  • en Genetic and antigenic characterization of H5, H6 and H9 avian influenza viruses circulating in live bird markets with intervention in the center part of Vietnam
Creator
    • en Duc-Huy Chu
    • en Hiono, Takahiro
    • en Ogasawara, Kohei
    • en Lam Thanh Nguyen
    • en Long Van Nguyen
    • en Tien Ngoc Nguyen
    • en Thuy Thu Nguyen
    • en Dong Van Pham
    • en Dang Hoang Nguyen
    • en Tho Dang Nguyen
    • en Thanh Long To
    • en Hung Van Nguyen
Accessrights open access
Rights
  • en ©2016, Elsevier. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/
  • http://creativecommons.org/licenses/by-nc-nd/4.0/
  • en Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
Subject
  • Other en Avian influenza
  • Other en Antigenic analysis
  • Other en Phylogenetic analysis
  • Other en Live bird market
  • Other en Surveillance
  • NDC 649
Description
  • Abstract en A total of 3,045 environmental samples and oropharyngeal and cloacal swabs from apparently healthy poultry have been collected at three live bird markets (LBMs) at which practices were applied to reduce avian influenza (AI) virus transmission (intervention LBMs) and six conventional LBMs (non-intervention LBMs) in Thua Thien Hue province in 2014 to evaluate the efficacy of the intervention LBMs. The 178 AI viruses, including H3 (19 viruses), H4 (2), H5 (8), H6 (30), H9 (114), and H11 (5), were isolated from domestic ducks, muscovy ducks, chickens, and the environment. The prevalence of AI viruses in intervention LBMs (6.1%; 95% CI: 5.0-7.5) was similar to that in non-intervention LBMs (5.6%; 95% CI: 4.5-6.8; x(2) = 0.532; df = 1; P = 0.53) in the study area. Eight H5N6 highly pathogenic avian influenza (HPAI) viruses were isolated from apparently healthy ducks, muscovy ducks, and an environmental sample in an intervention LBM. The hemagglutinin genes of the H5N6 HPAI viruses belonged to the genetic Glade 23.4.4, and the antigenicity of the H5N6 HPAI viruses differed from the H5N1 HPAI viruses previously circulating in Vietnam. Phylogenetic and antigenic analyses of the H6 and H9 viruses isolated in both types of LBMs revealed that they were closely related to the viruses isolated from domestic birds in China, Group II of H6 viruses and Y280 lineage of H9 viruses. These results indicate that the interventions currently applied in LBMs are insufficient to control AI. A risk analysis should be conducted to identify the key factors contributing to Al virus prevalence in intervention LBMs. (C) 2016 Elsevier B.V. All rights reserved.
Publisher en Elsevier
Date
    Issued2016-08-31
Language
  • eng
Resource Type journal article
Version Type AM
Identifier HDL http://hdl.handle.net/2115/67102
Relation
  • isVersionOf DOI https://doi.org/10.1016/j.vetmic.2016.07.016
  • PMID 27527783
Journal
    • PISSN 0378-1135
    • EISSN 1873-2542
    • NCID AA00883633
      • en Veterinary Microbiology
      • Volume Number192 Page Start194 Page End203
File
Oaidate 2023-07-26